Hentriacontane Reference: 29776-1 An alkane with anti-inflammatory activity; reduces LPS-induced TNF-α, IL-6, and IL-1β production in RAW 264.7 cells; reduces LPS-induced TNF-α, IL-6 and IL-1β production in whole blood and carrageenan-induced paw edema in mice
Ch 55 Reference: 18658-1 A synthetic analog of retinoic acid that binds to retinoic acid receptors with similar efficiency as retinoic acid (Kis in the nM range) yet does not display affinity for cellular retinoic acid-binding protein (Ki = 540 µM)
Hentriacontane Reference: 29776-250 An alkane with anti-inflammatory activity; reduces LPS-induced TNF-α, IL-6, and IL-1β production in RAW 264.7 cells; reduces LPS-induced TNF-α, IL-6 and IL-1β production in whole blood and carrageenan-induced paw edema in mice
Ch 55 Reference: 18658-10 A synthetic analog of retinoic acid that binds to retinoic acid receptors with similar efficiency as retinoic acid (Kis in the nM range) yet does not display affinity for cellular retinoic acid-binding protein (Ki = 540 µM)
Hentriacontane Reference: 29776-500 An alkane with anti-inflammatory activity; reduces LPS-induced TNF-α, IL-6, and IL-1β production in RAW 264.7 cells; reduces LPS-induced TNF-α, IL-6 and IL-1β production in whole blood and carrageenan-induced paw edema in mice
Ch 55 Reference: 18658-25 A synthetic analog of retinoic acid that binds to retinoic acid receptors with similar efficiency as retinoic acid (Kis in the nM range) yet does not display affinity for cellular retinoic acid-binding protein (Ki = 540 µM)
Betamethasone 21-phosphate (sodium salt hydrate) Reference: 29778-1 A synthetic glucocorticoid; prevents increases in macrophage and eosinophil numbers in BALF and decreases blood leukocyte numbers in a guinea pig model of parainfluenza-3 viral infection at 8 mg/kg; inhibits cell infiltration into the aqueous humor in a rat model of endotoxin-induced uveitis when administered topically or subcutaneously at doses of 0.01-1% or 1 mg/kg, respectively; increases maximal lung pressure volume curves in fetal sheep when administered to pregnant ewes at 0.75 gestation at doses of 80 and 170 µg/kg; increases body weight, impairs learning and memory, increases anxiolytic behavior, and reduces hippocampal neurogenesis in CD-1 mice but reduces body weight and increases neurogenesis with no effect on anxiety in high-anxiety DBA/2 mice when administered at a dose of approximately 25 mg/kg per day in the drinking water for seven weeks
Ch 55 Reference: 18658-5 A synthetic analog of retinoic acid that binds to retinoic acid receptors with similar efficiency as retinoic acid (Kis in the nM range) yet does not display affinity for cellular retinoic acid-binding protein (Ki = 540 µM)