Category: Reagents

Active filters

Zatebradine (hydrochloride)

Reference: 18608-5

Blocks If currents through HCN channels in sinoatrial node cells (IC50s = 1.83, 2.21, 1.9, and 1.88 µM, respectively for HCN1-4 in vitro); reduces heart rate from 600 to 200 beats per minute with an ED50 value of 1.8 mg/kg and induces increasing arrhythmia at concentrations >10 mg/kg when assessed through telemetric ECG recording in mice

Zatebradine (hydrochloride)

Reference: 18608-50

Blocks If currents through HCN channels in sinoatrial node cells (IC50s = 1.83, 2.21, 1.9, and 1.88 µM, respectively for HCN1-4 in vitro); reduces heart rate from 600 to 200 beats per minute with an ED50 value of 1.8 mg/kg and induces increasing arrhythmia at concentrations >10 mg/kg when assessed through telemetric ECG recording in mice

PF 06465469

Reference: B5691-10

inhibitor of interleukin-2 inducible T cell kinase (ITK) and Bruton's tyrosine kinase (BTK)

2-Aminopurine (hydrochloride)

Reference: 18609-100

A fluorescent analog of guanosine and adenosine that is used as a site-specific probe of nucleic acid structure and dynamics, such as studies of base stacking interactions and DNA base flipping; ex/em = 320/381 nm, respectively, when adjusted to reduce interference with DNA base absorption as well as tryptophan fluorescence; inhibits PKR

PF 06465469

Reference: B5691-50

inhibitor of interleukin-2 inducible T cell kinase (ITK) and Bruton's tyrosine kinase (BTK)

2-Aminopurine (hydrochloride)

Reference: 18609-250

A fluorescent analog of guanosine and adenosine that is used as a site-specific probe of nucleic acid structure and dynamics, such as studies of base stacking interactions and DNA base flipping; ex/em = 320/381 nm, respectively, when adjusted to reduce interference with DNA base absorption as well as tryptophan fluorescence; inhibits PKR

Back to top