Category: Reagents

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Reference: 19445-2,5

Inhibits PANC-1 cell survival in nutrient-deprived media at a 100-fold lower concentration than that required for cells maintained in nutrient-rich media

Reference: A1302-5.1

Selective IGF-1R/IR inhibitor

Reference: 19450-2,5

An inhibitor of the PTPs that blocks phosphorylation of CD45 and VHR (IC50s = 54 and 2 µM, respectively) and arrests cell cycle progress at the G1/S transition; also inhibits heparanase (IC50 = 17 µM), an endo-β-D-glucuronidase involved in tumor cell invasion and angiogenesis

Reference: A1302-50

Selective IGF-1R/IR inhibitor

Reference: 20133-2,5

An antibiotic that inhibits growth in various tumor cell lines (IC50s = 1-5 µM) by activating caspases 8 and 3