Category: Protein

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Reference: GTX00274-pro
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This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in...
Reference: GTX00275-pro
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The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa...
Reference: GTX00276-pro
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This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the...
Reference: GTX00277-pro
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The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of...
Reference: GTX00278-pro
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This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin...
Reference: GTX00279-pro
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The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory...
Reference: GTX00280-pro
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This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is...
Reference: GTX00283-pro
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This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that...
Reference: GTX00286-pro
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This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded...
Reference: GTX00287-pro
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This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This...
Reference: GTX00288-pro
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This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This...
Reference: GTX00290-pro
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The interleukin 2 receptor is composed of alpha and beta subunits. The beta subunit encoded by this gene is very homologous to the human beta subunit and also shows structural similarity to other cytokine receptors....
Reference: GTX00291-pro
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This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. The encoded precursor protein undergoes proteolytic cleavage to produce a disulfide-linked...
Reference: GTX00293-pro
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The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase...
Reference: GTX00295-pro
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This gene encodes a member of the fibroblast growth factor family. The encoded protein regulates phosphate homeostasis and vitamin D metabolism. Mutation of the related gene in humans causes autosomal dominant...
Reference: GTX00296-pro
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD...
Reference: GTX00305-pro
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This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous...
Reference: GTX00306-pro
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This gene encodes a member of the glycosyl hydrolase 2 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme,...
Reference: GTX00308-pro
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD...
Reference: GTX00309-pro
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This gene encodes a liver-specific mitochondrial enzyme that catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Regulated by glucocorticoid and polypeptide hormones, this genes expression is affected...
Reference: GTX00314-pro
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This gene encodes a key enzyme of the fibrinolytic pathway. The encoded protein undergoes proteolytic processing by plasmin to generate a heterodimeric serine protease that cleaves the proenzyme plasminogen to produce...
Reference: GTX00321-pro
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD...
Reference: GTX00322-pro
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The protein encoded by this gene is a member of the nerve growth factor family. It is involved in the growth, differentiation and survival of specific types of developing neurons both in the central nervous system...
Reference: GTX00325-pro
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Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase that...
Reference: GTX00327-pro
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This gene encodes epidermal growth factor (EGF), the founding member of the EGF family of growth factors that are implicated in cell proliferation and differentiation. The encoded protein can localize to the membrane...
Reference: GTX00331-pro
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This gene encodes a member of the small leucine-rich proteoglycan family. The encoded protein is an extracellular matrix protein that modulates the transforming growth factor-beta signaling pathway, regulating...
Reference: GTX00333-pro
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This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. This gene is predominantly expressed in the liver and the...
Reference: GTX00341-pro
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a cytokine involved in development and possibly in neurodegenerative processes [RGD, Feb 26]
Reference: GTX00342-pro
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acts as a cytokine; binds TNF receptors; plays a role in regulation of cell proliferation, induction of apoptosis, and inflammatory response [RGD, Feb 26]
Reference: GTX00343-pro
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This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular...
Reference: GTX00346-pro
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binds GTPase activating protein IQGAP1; may play a role in cell membrane rearrangement [RGD, Feb 26]
Reference: GTX00355-pro
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monooxygenase that plays a role in dioxin metabolism and detoxification which is 3-methylcholanthrene-inducible [RGD, Feb 26]
Reference: GTX00356-pro
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multifunctional enzyme thought to have scavenger function; able to neutralize harmful metabolites from foreign substances [RGD, Feb 26]
Reference: GTX00357-pro
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calcium-dependent protease that may be involved in experimental allergic encephalomyelitis (EAE) [RGD, Feb 26]
Reference: GTX00358-pro
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calcium-dependent protease that may be involved in experimental allergic encephalomyelitis (EAE) [RGD, Feb 26]
Reference: GTX00359-pro
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catalyzes the hydrolysis of arginine to ornithine and urea in arginine metabolism; regulates nitric oxide production [RGD, Feb 26]
Reference: GTX00360-pro
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This gene encodes a member of the TGF-beta (transforming growth factor-beta) family of proteins. The encoded preproprotein is proteolytically processed to generate an N-terminal propeptide and a C-terminal subunit....
Reference: GTX00362-pro
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protein may play a role in cellular growth control, viability and differentiation; high expression levels may induce apoptosis [RGD, Feb 26]
Reference: GTX00363-pro
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chemokine that binds its receptor CX3CR1; induces chemotaxis and increased intracellular calcium levels in microglia [RGD, Feb 26]
Reference: GTX00366-pro
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Th2-type cytokine; may be involved in inflammatory response in eosinophils [RGD, Feb 26]
Reference: GTX00367-pro
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plays a role in the development of hippocampal long term potentiation; involved in regulation of synaptic plasticity [RGD, Feb 26]
Reference: GTX00368-pro
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cytokine; involved in inflammatory and immune responses [RGD, Feb 26]
Reference: GTX00369-pro
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catalyzes the conversion of L-ornithine to putrescine [RGD, Feb 26]
Reference: GTX00370-pro
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promotes reduction of surface tension in the lung [RGD, Feb 26]
Reference: GTX00373-pro
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binds the epidermal growth factor receptor; may play a role in MAP kinase mediated signaling pathways [RGD, Feb 26]

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