Recombinant Human PlGF-3 Reference: GFH198-25 Placenta Growth Factor (PlGF) is a member of the Vascular Endothelial Growth Factor (VEGF) / Platelet-Derived Growth Factor (PDGF) family of growth factors that share a conserved pattern of eight cysteines. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. These growth factors induce monocyte activation, migration, and production of inflammatory cytokines and VEGF. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 is an angiogenic factor, which promotes endothelial cell growth and angiogenesis, being expressed exclusively in the placenta.
Neuroligin 2 blocking peptide Reference: GTX89107-PEP This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 28]
Recombinant Human PlGF-3 Reference: GFH198-100 Placenta Growth Factor (PlGF) is a member of the Vascular Endothelial Growth Factor (VEGF) / Platelet-Derived Growth Factor (PDGF) family of growth factors that share a conserved pattern of eight cysteines. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. These growth factors induce monocyte activation, migration, and production of inflammatory cytokines and VEGF. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 is an angiogenic factor, which promotes endothelial cell growth and angiogenesis, being expressed exclusively in the placenta.
SHP1 (internal region) blocking peptide Reference: GTX89108-PEP The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 28]
Recombinant Human PlGF-3 Reference: GFH198-1000 Placenta Growth Factor (PlGF) is a member of the Vascular Endothelial Growth Factor (VEGF) / Platelet-Derived Growth Factor (PDGF) family of growth factors that share a conserved pattern of eight cysteines. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. These growth factors induce monocyte activation, migration, and production of inflammatory cytokines and VEGF. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 is an angiogenic factor, which promotes endothelial cell growth and angiogenesis, being expressed exclusively in the placenta.
Perilipin 1 blocking peptide Reference: GTX89109-PEP The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 29]
Recombinant Human PlGF-3 (Animal-Free) Reference: GFH198AF-5 Placenta Growth Factor (PlGF) is a member of the Vascular Endothelial Growth Factor (VEGF) / Platelet-Derived Growth Factor (PDGF) family of growth factors that share a conserved pattern of eight cysteines. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. These growth factors induce monocyte activation, migration, and production of inflammatory cytokines and VEGF. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 is an angiogenic factor, which promotes endothelial cell growth and angiogenesis, being expressed exclusively in the placenta.
PDIA2 / PDIP blocking peptide Reference: GTX89110-PEP Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 [PubMed 856191]).[supplied by OMIM, Mar 28]
Recombinant Human PlGF-3 (Animal-Free) Reference: GFH198AF-25 Placenta Growth Factor (PlGF) is a member of the Vascular Endothelial Growth Factor (VEGF) / Platelet-Derived Growth Factor (PDGF) family of growth factors that share a conserved pattern of eight cysteines. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. These growth factors induce monocyte activation, migration, and production of inflammatory cytokines and VEGF. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 is an angiogenic factor, which promotes endothelial cell growth and angiogenesis, being expressed exclusively in the placenta.
Kallikrein 5 blocking peptide Reference: GTX89113-PEP Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 28]
Recombinant Human PlGF-3 (Animal-Free) Reference: GFH198AF-100 Placenta Growth Factor (PlGF) is a member of the Vascular Endothelial Growth Factor (VEGF) / Platelet-Derived Growth Factor (PDGF) family of growth factors that share a conserved pattern of eight cysteines. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. These growth factors induce monocyte activation, migration, and production of inflammatory cytokines and VEGF. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 is an angiogenic factor, which promotes endothelial cell growth and angiogenesis, being expressed exclusively in the placenta.