Recombinant Human NGF-β Reference: GFH38-20 Nerve Growth Factor β (NGF-β) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. NGF-β signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. NGF-β is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat NGF-β proteins are cross-reactive.
CRHR1 (aa 107 - 117) blocking peptide Reference: GTX88961-PEP This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Readthrough transcription also exists between this gene and upstream GeneID:41884 (ADP-ribosylation factor 3 pseudogene), and the readthrough transcripts encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Dec 214]
Recombinant Human NGF-β Reference: GFH38-100 Nerve Growth Factor β (NGF-β) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. NGF-β signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. NGF-β is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat NGF-β proteins are cross-reactive.
GIRK2 blocking peptide Reference: GTX88962-PEP This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 215]
Recombinant Human NGF-β Reference: GFH38-1000 Nerve Growth Factor β (NGF-β) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. NGF-β signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. NGF-β is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat NGF-β proteins are cross-reactive.
B3GNT2 blocking peptide Reference: GTX88963-PEP This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. [provided by RefSeq, Jul 28]
Recombinant Human NGF-β (Animal-Free) Reference: GFH38AF-5 Nerve Growth Factor β (NGF-β) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. NGF-β signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. NGF-β is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat NGF-β proteins are cross-reactive.
Lactate Dehydrogenase C (aa 217 - 231) blocking peptide Reference: GTX88966-PEP Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region. [provided by RefSeq, Jul 28]
Recombinant Human NGF-β (Animal-Free) Reference: GFH38AF-20 Nerve Growth Factor β (NGF-β) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. NGF-β signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. NGF-β is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat NGF-β proteins are cross-reactive.
RPL17 blocking peptide Reference: GTX88967-PEP Ribosomes, the organelles that catalyze protein synthesis, consist of a small 4S subunit and a large 6S subunit. Together these subunits are composed of 4 RNA species and approximately 8 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 6S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. [provided by RefSeq, Dec 21]
Recombinant Human NGF-β (Animal-Free) Reference: GFH38AF-100 Nerve Growth Factor β (NGF-β) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. NGF-β signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. NGF-β is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat NGF-β proteins are cross-reactive.