Category: Proteins & Peptides

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Reference: 32086-50

Source: Recombinant human C-terminal His-tagged VISTA expressed in HEK293 cells • Amino acids: 33-194 • MW: 19.6 kDa

Reference: GTX32143-PEP

This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 211]

Reference: GTX32144-PEP

Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 24]

Reference: 32088-20

Source: Active recombinant human C-terminal His-tagged IDS expressed in HEK293 cells • Amino acids: 26-550 • MW: 61 kDa

Reference: GTX32145-PEP

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 29]

Reference: 32088-50

Source: Active recombinant human C-terminal His-tagged IDS expressed in HEK293 cells • Amino acids: 26-550 • MW: 61 kDa