PCSK9-DyLight™ 633 Reference: 30592-50 Source: Active recombinant N-terminal His-tagged enzyme expressed in HEK293 cells. Conjugated to DyLight™ 633 • Amino acids: 1-692 (full length) • MW: 13.8 kDa prodomain + 59 kDa mature form
FOXA1 blocking peptide Reference: GTX31874-PEP This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq, Jul 28]
TGF-β1 (human, recombinant) Reference: 30606-10 Source: Recombinant human C-terminal His-tagged TGF-β1 expressed in HEK293 cells • Amino acids: 1-390 (full length) • MW: 42.4 kDa for LAP-bound TGF-β1
FOXA2 blocking peptide Reference: GTX31875-PEP This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 28]
TGF-β1 (human, recombinant) Reference: 30606-20 Source: Recombinant human C-terminal His-tagged TGF-β1 expressed in HEK293 cells • Amino acids: 1-390 (full length) • MW: 42.4 kDa for LAP-bound TGF-β1
KREMEN1 blocking peptide Reference: GTX31876-PEP This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 28]
TGF-β1 (human, recombinant) Reference: 30606-50 Source: Recombinant human C-terminal His-tagged TGF-β1 expressed in HEK293 cells • Amino acids: 1-390 (full length) • MW: 42.4 kDa for LAP-bound TGF-β1
SLC27A6 blocking peptide Reference: GTX31878-PEP This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 28]
IFN-β (human, recombinant) Reference: 31528-100 Source: Active recombinant human IFN-β expressed in CHO cells • Amino acids: 22-187 • MW: 20 kDa
TORC2 blocking peptide Reference: GTX31879-PEP This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 21]
IFN-β (human, recombinant) Reference: 31528-20 Source: Active recombinant human IFN-β expressed in CHO cells • Amino acids: 22-187 • MW: 20 kDa