Histone (calf thymus) Reference: 16736-10 A mixture of H1, H2a, H2b, H3, and H4 histones isolated from calf thymus
APC1 blocking peptide Reference: GTX31801-PEP This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 211]
Histone (calf thymus) Reference: 16736-100 A mixture of H1, H2a, H2b, H3, and H4 histones isolated from calf thymus
Histone (calf thymus) Reference: 16736-50 A mixture of H1, H2a, H2b, H3, and H4 histones isolated from calf thymus
SAE1 blocking peptide Reference: GTX31803-PEP Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 61912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 99283]).[supplied by OMIM, Mar 21]
COX-1 (human recombinant) Reference: 17616-5 Peptide sequence: 24-599 (full-length) • Source: Recombinant N-terminal His-tagged protein expressed using the baculovirus system • Mr: ~70 kDa
UBA2 blocking peptide Reference: GTX31804-PEP Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 61912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 99283]).[supplied by OMIM, Mar 21]
Citrullinated Histone H3 (human, recombinant) Reference: 17926-100 Source: Recombinant protein expressed in E. coli, citrullinated with human recombinant PAD4 • MW: 15.5 kDa
SUMO3 blocking peptide Reference: GTX31805-PEP SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 22 [PubMed 1238354]).[supplied by OMIM, Mar 28]
Citrullinated Histone H4 (human, recombinant) Reference: 17927-100 Source: Recombinant protein expressed in E. coli, citrullinated with human recombinant PAD4 • Amino acids: 1-103 (full-length) • MW: 11.5 kDa
FOXO1 blocking peptide Reference: GTX31806-PEP This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 28]