BRD4 bromodomain 1 (human, recombinant, GST-tagged) Reference: 11068-100 Source: Recombinant human N-terminal GST-tagged BRD4 bromodomain 1 expressed in E. coli • Amino acids: 49-170 • MW: 41.4 kDa
Caspase 7 blocking peptide Reference: GTX31705-PEP This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 1, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 212]
BRD2 bromodomains 1 and 2 (human, recombinant) Reference: 11069-1 Source: Recombinant GST-tagged protein expressed in E. coli • Amino acids: 65-459 • MW: 71.2 kDa
Caspase 6 blocking peptide Reference: GTX31707-PEP This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 1, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 28]
BRD2 bromodomains 1 and 2 (human, recombinant) Reference: 11069-100 Source: Recombinant GST-tagged protein expressed in E. coli • Amino acids: 65-459 • MW: 71.2 kDa
MCL1 blocking peptide Reference: GTX31708-PEP This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 21]
BRD2 bromodomain 2 (human, recombinant) Reference: 11070-1 Source: Recombinant N-terminal GST-tagged BRD2 bromodomain 2 expressed in E. coli • AA: 339-459 • MW: 42.4 kDa
MCL1 blocking peptide Reference: GTX31709-PEP This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 21]
BRD2 bromodomain 2 (human, recombinant) Reference: 11070-100 Source: Recombinant N-terminal GST-tagged BRD2 bromodomain 2 expressed in E. coli • AA: 339-459 • MW: 42.4 kDa
BRD2 bromodomain 1 (human, recombinant) Reference: 11071-1 Source: Recombinant N-terminal GST-tagged protein expressed in E. coli • MW: 42.4 kDa
Rheb blocking peptide Reference: GTX31712-PEP This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 1 and one on chromosome 22. [provided by RefSeq, Jul 28]