IL-1 beta, rat recombinant Reference: P1019-.01 IL-1β, proinflammatory cytokine, expressed in E.Coli.
ASAH1 blocking peptide Reference: GTX31356-PEP This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 28]
IL-1 beta, rat recombinant Reference: P1019-.05 IL-1β, proinflammatory cytokine, expressed in E.Coli.
EDG1 blocking peptide Reference: GTX31360-PEP The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. [provided by RefSeq, Jul 28]
OTUD5 blocking peptide Reference: GTX31361-PEP This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 28]
IL-2, human recombinant Reference: P1020-.05 IL-2, lymphoid cell growth factor, expressed in E.Coli, active in murine and human T cells.
IL-2, human recombinant Reference: P1020-1 IL-2, lymphoid cell growth factor, expressed in E.Coli, active in murine and human T cells.
IL-3, human recombinant Reference: P1021-.01 IL-3, pleiotropic cytokine, expressed in E.Coli, species-specific.
DISP2 blocking peptide Reference: GTX31364-PEP The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched. [provided by RefSeq, Jul 28]