GM-CSF, rat recombinant Reference: P1014-1 GM-CSF, pleiotropic cytokine, expressed in E.Coli, active in mouse cells.
TNPO3 blocking peptide Reference: GTX31343-PEP The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 21]
IFN-gamma, murine recombinant Reference: P1015-.02 IFN-γ, proinflammatory cytokine, expressed in E.Coli, suitable for cell culture.
TNPO3 blocking peptide Reference: GTX31344-PEP The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 21]
IFN-gamma, murine recombinant Reference: P1015-.1 IFN-γ, proinflammatory cytokine, expressed in E.Coli, suitable for cell culture.
Wnt10a blocking peptide Reference: GTX31345-PEP The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq, Jul 28]
IFN-gamma, murine recombinant Reference: P1015-1 IFN-γ, proinflammatory cytokine, expressed in E.Coli, suitable for cell culture.
IGF-1, human recombinant Reference: P1016-.02 IGF-1, endocrine hormone, expressed in E.Coli, cross-species reactivity.
CPEB1 blocking peptide Reference: GTX31347-PEP This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 28]
IGF-1, human recombinant Reference: P1016-.1 IGF-1, endocrine hormone, expressed in E.Coli, cross-species reactivity.
GDF6 blocking peptide Reference: GTX31348-PEP This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. It is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation. [provided by RefSeq, Jul 28]