Recombinant Human Pleiotrophin - 50 µg

Pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1), also known as PTN is a growth, differentiation inducing cytokine,1 and neurite extension promoting polypeptide which is highly expressed in brain and in tissues derived from mesenchyme.2 PTN is produced by many different human cancers and stimulates tumor blood vessel formation when it is expressed in malignant cancer cells.3 It is expressed in many types of cancer, such as gliomas, melanomas, meningiomas, neuroblastomas, choriocarcinomas, leukemias and cancers of pancreas, prostate, stomach, colon, breast, ovaries and lungs.4