187-1, N-WASP inhibitor TFA

187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein.
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Reference:
HY-P1045A
Product Details
HY-P1045A

Data sheet

Size
Multiple sizes
Reactivity
Arp2/3 Complex
Application
COVID-19-immunoregulation

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