Quote Recombinant Human U1 small nuclear ribonucleoprotein 70 kDa(SNRNP70),partial
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
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Reference:
CSB-EP714018HU1a0_1
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