Quote Recombinant Bovine Agouti-signaling protein(ASIP)
Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment)
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Reference:
CSB-EP639982BO_1
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