Quote Recombinant Saccharomyces cerevisiae Nicotinamidase(PNC1)
Catalyzes the deamidation of nicotinamide, an early step in the NAD+ salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate.
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Reference:
CSB-EP346834SVG_20
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