Quote Recombinant Aspergillus clavatus Ribonuclease clavin(cla)
Clavin has the same substrate specificity as alpha-sarcin. It is specific for purines in both single- and double-stranded RNA. Its toxic action on eukaryotic cells is the result of cleavage of a single phosphodiester bond in the 60S subunit of ribosomes.
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Reference:
CSB-EP316109AVC_1
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