Quote Recombinant Human Melanoma antigen preferentially expressed in tumors(PRAME)
Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
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Reference:
CSB-EP018603HU_100
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