Quote Recombinant Human Guanylate cyclase soluble subunit alpha-2(GUCY1A2),partial
Has guanylyl cyclase on binding to the beta-1 subunit.
Isoform 2 acts as a negative regulator of guanylyl cyclase activity as it forms non-functional heterodimers with the beta subunits.
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Reference:
CSB-EP010049HU1_100
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