Quote Recombinant Human Growth arrest and DNA damage-inducible protein GADD45 alpha(GADD45A)
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity . Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
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Reference:
CSB-EP009161HU_100
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