Quote Recombinant Human Bone morphogenetic protein receptor type-1A(BMPR1A),partial
On ligand binding, forms a receptor complex consisting of two type II and two type I transmbrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. Positively regulates chondrocyte differentiation through GDF5 interaction .
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Reference:
CSB-EP002748HU_20
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