Bla g 4 (cockroach) (rec.)
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Causes an allergic reaction in human. Binds to IgE. Induces histamine release from basophils of profilin-allergic patients. Food allergen: Yes. Probable ligand-binding protein.
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Reference:
YIF-LF-P0514A
Brand: