Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (His)

UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an ATP-dependent mechanism where ATP is hydrolyzed to AMP and PPi, a ubiquitin C-terminal adenylate intermediate is formed, then transferred to the E1's active site cysteine through a thioester bond. This thioester is then transferable to an E2 conjugating enzyme's active site cysteine.
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€0.00 (tax incl.)
Reference:
SBB-CE0058-C050
Brand:
AdipoGen
Product Details
SBB-CE0058-C050

Data sheet

Host
Sf21 cells
URL - Product
https://www.adipogen.com/productmanagement/resource/download/type/sheet/id/17262

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