HSH2D blocking peptide

T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 18688) and a costimulatory signal provided primarily by CD28 (MIM 18676) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 23 [PubMed 1296172]).[supplied by OMIM, Mar 28]

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