Quote Human OBFC1 protein, His tag
OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 29 [PubMed 19119139]). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF16; MIM 61313) (Miyake et al., 29 [PubMed 1985413]).[supplied by OMIM, Nov 29]
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Reference:
GTX68750-pro
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