Quote Human Flt3 Ligand protein (active)
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 18691)-positive classical DCs and their CD13 (ITGAE; MIM 64682)-positive tissue counterparts (summary by Sathaliyawala et al., 21 [PubMed 2933441]).[supplied by OMIM, Jan 211]
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Reference:
GTX48446-pro
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