Almorexant (hydrochloride)

An orexin 1 and orexin 2 receptor antagonist (Kis = 4.7 and 0.9 nM, respectively); decreases the latency to persistent NREM and REM sleep and increases the duration of NREM and REM sleep in male rats when administered at a dose of 100 mg/kg; does not impair spatial learning and memory in the Morris water maze at 300 mg/kg