C24 (2’(R)-hydroxy) Phytoceramide (t18:0/24:0)

A naturally occurring sphingolipid; inhibits LPS-induced NO production in RAW 264.7 macrophages (IC50 = 19 μg/ml), as well as increases in COX-2 and iNOS levels; increases production of CXCL8, CXCL1, CCL2, and CCL20 in HUVECs in a concentration-dependent manner; a hydroxylated form of C24 phytoceramide