Cayman Chemical (161)

CCG-100602

Reference: 10787-50

€0.00 (tax incl.)

Inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC3 prostate cancer cells with an IC50 value of 9.8 µM

A potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively); has antipsychotic-like activities in rats and Cebus monkeys; enhances...

Xanomeline (oxalate)

Reference: 10790-10

€0.00 (tax incl.)

A potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively); has antipsychotic-like activities in rats and Cebus monkeys; enhances...

Xanomeline (oxalate)

Reference: 10790-5

€0.00 (tax incl.)

A potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively); has antipsychotic-like activities in rats and Cebus monkeys; enhances...

CAY10647

Reference: 10791-1

€0.00 (tax incl.)

An aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg); binds to tubulin (Ki = 3.4 μM)...

CAY10647

Reference: 10791-10

€0.00 (tax incl.)

An aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg); binds to tubulin (Ki = 3.4 μM)...

CAY10647

Reference: 10791-5

€0.00 (tax incl.)

An aryl-benzoyl-imidazole which prevents proliferation of multidrug resistant cancer cells in vitro (IC50 = 28-63 nM) and inhibits melanoma xenograph tumor growth in vivo (10-30 mg/kg); binds to tubulin (Ki = 3.4 μM)...

SC 26196

Reference: 10792-1

€0.00 (tax incl.)

A selective inhibitor of Δ6 desaturase (IC50 = 0.2 µM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to AA; orally active in vivo, decreasing edema in the carrageenan paw edema...

SC 26196

Reference: 10792-10

€0.00 (tax incl.)

A selective inhibitor of Δ6 desaturase (IC50 = 0.2 µM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to AA; orally active in vivo, decreasing edema in the carrageenan paw edema...

SC 26196

Reference: 10792-25

€0.00 (tax incl.)

A selective inhibitor of Δ6 desaturase (IC50 = 0.2 µM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to AA; orally active in vivo, decreasing edema in the carrageenan paw edema...

SC 26196

Reference: 10792-5

€0.00 (tax incl.)

A selective inhibitor of Δ6 desaturase (IC50 = 0.2 µM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to AA; orally active in vivo, decreasing edema in the carrageenan paw edema...

AG-879

Reference: 10793-10

€0.00 (tax incl.)

A tyrphostin compound that inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM),...

AG-879

Reference: 10793-25

€0.00 (tax incl.)

A tyrphostin compound that inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM),...

AG-879

Reference: 10793-5

€0.00 (tax incl.)

A tyrphostin compound that inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM),...

AG-879

Reference: 10793-50

€0.00 (tax incl.)

A tyrphostin compound that inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM),...

22-Oxacalcitriol

Reference: 10794-1

€0.00 (tax incl.)

An analog of calcitriol that, like calcitriol, is a receptor-active form of vitamin D3 which effectively blocks PTH synthesis; inhibits human keratinocyte proliferation and is beneficial in treating psoriasis; blocks...

22-Oxacalcitriol

Reference: 10794-5

€0.00 (tax incl.)

An analog of calcitriol that, like calcitriol, is a receptor-active form of vitamin D3 which effectively blocks PTH synthesis; inhibits human keratinocyte proliferation and is beneficial in treating psoriasis; blocks...

22-Oxacalcitriol

Reference: 10794-500

€0.00 (tax incl.)

An analog of calcitriol that, like calcitriol, is a receptor-active form of vitamin D3 which effectively blocks PTH synthesis; inhibits human keratinocyte proliferation and is beneficial in treating psoriasis; blocks...

CCG-50014

Reference: 10802-1

€0.00 (tax incl.)

An inhibitor of RGS4 (IC50 = 30 nM); blocks GTPase activity and Gα0-dependent translocation of RGS4 to the membrane

CCG-50014

Reference: 10802-10

€0.00 (tax incl.)

An inhibitor of RGS4 (IC50 = 30 nM); blocks GTPase activity and Gα0-dependent translocation of RGS4 to the membrane

CCG-50014

Reference: 10802-5

€0.00 (tax incl.)

An inhibitor of RGS4 (IC50 = 30 nM); blocks GTPase activity and Gα0-dependent translocation of RGS4 to the membrane

CAY10649

Reference: 10804-1

€0.00 (tax incl.)

A thiazolinone compound that directly inhibits 5-LO product formation in intact polymorphonuclear leukocytes and a soluble fraction of a S100 PMNL cell lysate (IC50s = 0.28 and 0.09 μM, respectively)

CAY10649

Reference: 10804-10

€0.00 (tax incl.)

A thiazolinone compound that directly inhibits 5-LO product formation in intact polymorphonuclear leukocytes and a soluble fraction of a S100 PMNL cell lysate (IC50s = 0.28 and 0.09 μM, respectively)

CAY10649

Reference: 10804-5

€0.00 (tax incl.)

A thiazolinone compound that directly inhibits 5-LO product formation in intact polymorphonuclear leukocytes and a soluble fraction of a S100 PMNL cell lysate (IC50s = 0.28 and 0.09 μM, respectively)

Coumarin Boronic Acid pinacolate ester

Reference: 10818-10

€0.00 (tax incl.)

A fluorescent probe for detection of peroxynitrite; a more soluble form of CBA; can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide; COH displays ex/em = 332/470 nm, respectively,

Coumarin Boronic Acid pinacolate ester

Reference: 10818-100

€0.00 (tax incl.)

A fluorescent probe for detection of peroxynitrite; a more soluble form of CBA; can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide; COH displays ex/em = 332/470 nm, respectively,

Coumarin Boronic Acid pinacolate ester

Reference: 10818-5

€0.00 (tax incl.)

A fluorescent probe for detection of peroxynitrite; a more soluble form of CBA; can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide; COH displays ex/em = 332/470 nm, respectively,

Coumarin Boronic Acid pinacolate ester

Reference: 10818-50

€0.00 (tax incl.)

A fluorescent probe for detection of peroxynitrite; a more soluble form of CBA; can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide; COH displays ex/em = 332/470 nm, respectively,

ABL 127

Reference: 10833-1

€0.00 (tax incl.)

A covalent inhibitor of PME-1 (IC50 = 4.2 nM); selectively inhibits PME-1 over 50 other serine hydrolases in MDA-MB-231 and HEK293T cell lysates at 10 μM; decreases proliferation of Ishikawa cells and migration of...

ABL 127

Reference: 10833-10

€0.00 (tax incl.)

A covalent inhibitor of PME-1 (IC50 = 4.2 nM); selectively inhibits PME-1 over 50 other serine hydrolases in MDA-MB-231 and HEK293T cell lysates at 10 μM; decreases proliferation of Ishikawa cells and migration of...

ABL 127

Reference: 10833-5

€0.00 (tax incl.)

A covalent inhibitor of PME-1 (IC50 = 4.2 nM); selectively inhibits PME-1 over 50 other serine hydrolases in MDA-MB-231 and HEK293T cell lysates at 10 μM; decreases proliferation of Ishikawa cells and migration of...

Guanabenz (hydrochloride)

Reference: 10851-100

€0.00 (tax incl.)

An α2-adrenergic receptor agonist (effective concentrations 10-100 nM) with hypotensive effects; competes for imidazoline I2-binding sites in brown adipose tissue (Ki = 97 nM)

Guanabenz (hydrochloride)

Reference: 10851-25

€0.00 (tax incl.)

An α2-adrenergic receptor agonist (effective concentrations 10-100 nM) with hypotensive effects; competes for imidazoline I2-binding sites in brown adipose tissue (Ki = 97 nM)

Guanabenz (hydrochloride)

Reference: 10851-50

€0.00 (tax incl.)

An α2-adrenergic receptor agonist (effective concentrations 10-100 nM) with hypotensive effects; competes for imidazoline I2-binding sites in brown adipose tissue (Ki = 97 nM)

Histone H4 Peptide Substrate (1-21)

Reference: 10854-1

€0.00 (tax incl.)

A target substrate for several of the histone modifying enzymes including lysine methyltransferases, arginine methyltransferases, acetyltransferases, and others

CAY10654

Reference: 10857-1

€0.00 (tax incl.)

A synthetic analog of natural AHLs that suppresses host immunity without inducing LasR; inhibits the proliferation of mouse peripheral blood leukocytes by concanavalin A (EC50 = 9.3 μM) without concurrent...

CAY10654

Reference: 10857-10

€0.00 (tax incl.)

A synthetic analog of natural AHLs that suppresses host immunity without inducing LasR; inhibits the proliferation of mouse peripheral blood leukocytes by concanavalin A (EC50 = 9.3 μM) without concurrent...

CAY10654

Reference: 10857-25

€0.00 (tax incl.)

A synthetic analog of natural AHLs that suppresses host immunity without inducing LasR; inhibits the proliferation of mouse peripheral blood leukocytes by concanavalin A (EC50 = 9.3 μM) without concurrent...

CAY10654

Reference: 10857-5

€0.00 (tax incl.)

A synthetic analog of natural AHLs that suppresses host immunity without inducing LasR; inhibits the proliferation of mouse peripheral blood leukocytes by concanavalin A (EC50 = 9.3 μM) without concurrent...

UNC669

Reference: 10875-10

€0.00 (tax incl.)

An inhibitor of the MBT domain of L3MBTL1 (IC50 = 6 µM)

UNC669

Reference: 10875-25

€0.00 (tax incl.)

An inhibitor of the MBT domain of L3MBTL1 (IC50 = 6 µM)

UNC669

Reference: 10875-5

€0.00 (tax incl.)

An inhibitor of the MBT domain of L3MBTL1 (IC50 = 6 µM)

UNC669

Reference: 10875-50

€0.00 (tax incl.)

An inhibitor of the MBT domain of L3MBTL1 (IC50 = 6 µM)

SC-66

Reference: 10876-10

€0.00 (tax incl.)

An allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt; inhibits Akt activity in HEK293T cells, promoting cell death; suppresses tumor growth in mice

SC-66

Reference: 10876-100

€0.00 (tax incl.)

An allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt; inhibits Akt activity in HEK293T cells, promoting cell death; suppresses tumor growth in mice

SC-66

Reference: 10876-25

€0.00 (tax incl.)

An allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt; inhibits Akt activity in HEK293T cells, promoting cell death; suppresses tumor growth in mice

SC-66

Reference: 10876-5

€0.00 (tax incl.)

An allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt; inhibits Akt activity in HEK293T cells, promoting cell death; suppresses tumor growth in mice

Histone H3 Peptide Substrate (1-21)

Reference: 10877-1

€0.00 (tax incl.)

A target substrate for several of the histone modifying enzymes including lysine methyltransferases, arginine methyltransferases, acetyltransferases, and others

JW 480

Reference: 10879-10

€0.00 (tax incl.)

A potent, selective inhibitor of KIAA1361 (IC50s = 20 nM in mouse brain membrane proteomes and 6-12 nM in human PC3 prostate cancer cell proteomes); reduces PC3 tumor xenograft growth in immune-deficient SCID mice at...

JW 480

Reference: 10879-25

€0.00 (tax incl.)

A potent, selective inhibitor of KIAA1361 (IC50s = 20 nM in mouse brain membrane proteomes and 6-12 nM in human PC3 prostate cancer cell proteomes); reduces PC3 tumor xenograft growth in immune-deficient SCID mice at...

JW 480

Reference: 10879-5

€0.00 (tax incl.)

A potent, selective inhibitor of KIAA1361 (IC50s = 20 nM in mouse brain membrane proteomes and 6-12 nM in human PC3 prostate cancer cell proteomes); reduces PC3 tumor xenograft growth in immune-deficient SCID mice at...

JW 480

Reference: 10879-50

€0.00 (tax incl.)

A potent, selective inhibitor of KIAA1361 (IC50s = 20 nM in mouse brain membrane proteomes and 6-12 nM in human PC3 prostate cancer cell proteomes); reduces PC3 tumor xenograft growth in immune-deficient SCID mice at...

HZ52

Reference: 10888-1

€0.00 (tax incl.)

A potent, reversible 5-LO inhibitor, blocking LTB4 synthesis with an IC50 value of 0.7 μM in intact human polymorphonuclear leukocytes; also attenuates LTB4 synthesis, prevents carrageenan-induced pleurisy, and...

HZ52

Reference: 10888-10

€0.00 (tax incl.)

A potent, reversible 5-LO inhibitor, blocking LTB4 synthesis with an IC50 value of 0.7 μM in intact human polymorphonuclear leukocytes; also attenuates LTB4 synthesis, prevents carrageenan-induced pleurisy, and...

HZ52

Reference: 10888-25

€0.00 (tax incl.)

A potent, reversible 5-LO inhibitor, blocking LTB4 synthesis with an IC50 value of 0.7 μM in intact human polymorphonuclear leukocytes; also attenuates LTB4 synthesis, prevents carrageenan-induced pleurisy, and...

HZ52

Reference: 10888-5

€0.00 (tax incl.)

A potent, reversible 5-LO inhibitor, blocking LTB4 synthesis with an IC50 value of 0.7 μM in intact human polymorphonuclear leukocytes; also attenuates LTB4 synthesis, prevents carrageenan-induced pleurisy, and...

SR 1001

Reference: 10922-1

€0.00 (tax incl.)

A synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist; inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs...

SR 1001

Reference: 10922-10

€0.00 (tax incl.)

A synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist; inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs...

SR 1001

Reference: 10922-25

€0.00 (tax incl.)

A synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist; inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs...

SR 1001

Reference: 10922-5

€0.00 (tax incl.)

A synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist; inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs...

Epothilone B

Reference: 10924-1

€0.00 (tax incl.)

A macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis; induces mitotic arrest...

Epothilone B

Reference: 10924-10

€0.00 (tax incl.)

A macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis; induces mitotic arrest...

Epothilone B

Reference: 10924-5

€0.00 (tax incl.)

A macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis; induces mitotic arrest...

GN25

Reference: 10948-10

€0.00 (tax incl.)

A 2-thio-dimethoxy naphthoquinone analog that blocks Snail binding to p53 and induces p53 expression in cancer cells in a K-Ras dependent manner

GN25

Reference: 10948-25

€0.00 (tax incl.)

A 2-thio-dimethoxy naphthoquinone analog that blocks Snail binding to p53 and induces p53 expression in cancer cells in a K-Ras dependent manner

GN25

Reference: 10948-5

€0.00 (tax incl.)

A 2-thio-dimethoxy naphthoquinone analog that blocks Snail binding to p53 and induces p53 expression in cancer cells in a K-Ras dependent manner

GN25

Reference: 10948-50

€0.00 (tax incl.)

A 2-thio-dimethoxy naphthoquinone analog that blocks Snail binding to p53 and induces p53 expression in cancer cells in a K-Ras dependent manner

1-NA-PP1

Reference: 10954-1

€0.00 (tax incl.)

A reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase; inhibits v-Src-as1,...

1-NA-PP1

Reference: 10954-10

€0.00 (tax incl.)

A reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase; inhibits v-Src-as1,...

1-NA-PP1

Reference: 10954-5

€0.00 (tax incl.)

A reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase; inhibits v-Src-as1,...

1-NA-PP1

Reference: 10954-50

€0.00 (tax incl.)

A reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase; inhibits v-Src-as1,...

VU0359595

Reference: 10955-1

€0.00 (tax incl.)

A highly selective inhibitor of PLD1 (IC50 = 3.7 nM) versus PLD2 (IC50 = 6.4 μM)

VU0359595

Reference: 10955-10

€0.00 (tax incl.)

A highly selective inhibitor of PLD1 (IC50 = 3.7 nM) versus PLD2 (IC50 = 6.4 μM)

VU0359595

Reference: 10955-25

€0.00 (tax incl.)

A highly selective inhibitor of PLD1 (IC50 = 3.7 nM) versus PLD2 (IC50 = 6.4 μM)

VU0359595

Reference: 10955-5

€0.00 (tax incl.)

A highly selective inhibitor of PLD1 (IC50 = 3.7 nM) versus PLD2 (IC50 = 6.4 μM)

Clofibrate

Reference: 10956-1

€0.00 (tax incl.)

A selective PPARα agonist; exhibits EC50 values of 50 and 55 µM for mouse and human PPARα, respectively; inactive at PPARδ at concentrations up to 100 µM,

Clofibrate

Reference: 10956-10

€0.00 (tax incl.)

A selective PPARα agonist; exhibits EC50 values of 50 and 55 µM for mouse and human PPARα, respectively; inactive at PPARδ at concentrations up to 100 µM,

Clofibrate

Reference: 10956-5

€0.00 (tax incl.)

A selective PPARα agonist; exhibits EC50 values of 50 and 55 µM for mouse and human PPARα, respectively; inactive at PPARδ at concentrations up to 100 µM,

Clofibrate

Reference: 10956-500

€0.00 (tax incl.)

A selective PPARα agonist; exhibits EC50 values of 50 and 55 µM for mouse and human PPARα, respectively; inactive at PPARδ at concentrations up to 100 µM,

Bisdemethoxycurcumin

Reference: 10960-10

€0.00 (tax incl.)

A natural demethoxy derivative of curcumin; activates macrophage phagocytosis and, with 1α,25-dihydroxy vitamin D3, stimulates amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC); suppresses...

Bisdemethoxycurcumin

Reference: 10960-25

€0.00 (tax incl.)

A natural demethoxy derivative of curcumin; activates macrophage phagocytosis and, with 1α,25-dihydroxy vitamin D3, stimulates amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC); suppresses...

Bisdemethoxycurcumin

Reference: 10960-5

€0.00 (tax incl.)

A natural demethoxy derivative of curcumin; activates macrophage phagocytosis and, with 1α,25-dihydroxy vitamin D3, stimulates amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC); suppresses...

Bisdemethoxycurcumin

Reference: 10960-50

€0.00 (tax incl.)

A natural demethoxy derivative of curcumin; activates macrophage phagocytosis and, with 1α,25-dihydroxy vitamin D3, stimulates amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC); suppresses...

Demethoxycurcumin

Reference: 10961-1

€0.00 (tax incl.)

A natural demethoxy derivative of curcumin; suppresses proliferation in cancer cells at 50-100 μM; down-regulates p300 and inhibits LPS-induced iNOS expression

Demethoxycurcumin

Reference: 10961-10

€0.00 (tax incl.)

A natural demethoxy derivative of curcumin; suppresses proliferation in cancer cells at 50-100 μM; down-regulates p300 and inhibits LPS-induced iNOS expression

Demethoxycurcumin

Reference: 10961-25

€0.00 (tax incl.)

A natural demethoxy derivative of curcumin; suppresses proliferation in cancer cells at 50-100 μM; down-regulates p300 and inhibits LPS-induced iNOS expression

Demethoxycurcumin

Reference: 10961-5

€0.00 (tax incl.)

A natural demethoxy derivative of curcumin; suppresses proliferation in cancer cells at 50-100 μM; down-regulates p300 and inhibits LPS-induced iNOS expression

CAY10669

Reference: 10974-1

€0.00 (tax incl.)

An inhibitor of the HAT PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid; dose dependently inhibits histone H4 acetylation in...

CAY10669

Reference: 10974-10

€0.00 (tax incl.)

An inhibitor of the HAT PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid; dose dependently inhibits histone H4 acetylation in...

CAY10669

Reference: 10974-5

€0.00 (tax incl.)

An inhibitor of the HAT PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid; dose dependently inhibits histone H4 acetylation in...

Zebularine

Reference: 10975-1

€0.00 (tax incl.)

A DNA methylation inhibitor that acts by forming a covalent complex with DNA methyltransferases (DNMTs); preferentially targets cancer cells demonstrating IC20 values of 20, 10, 20, and 5 μM for reducing proliferation...

Zebularine

Reference: 10975-10

€0.00 (tax incl.)

A DNA methylation inhibitor that acts by forming a covalent complex with DNA methyltransferases (DNMTs); preferentially targets cancer cells demonstrating IC20 values of 20, 10, 20, and 5 μM for reducing proliferation...

Zebularine

Reference: 10975-5

€0.00 (tax incl.)

A DNA methylation inhibitor that acts by forming a covalent complex with DNA methyltransferases (DNMTs); preferentially targets cancer cells demonstrating IC20 values of 20, 10, 20, and 5 μM for reducing proliferation...

16(R)-AFP 07 (free acid)

Reference: 10991-1

€0.00 (tax incl.)

An epimer of AFP 07

16(R)-AFP 07 (free acid)

Reference: 10991-5

€0.00 (tax incl.)

An epimer of AFP 07

16(R)-AFP 07 (free acid)

Reference: 10991-500

€0.00 (tax incl.)

An epimer of AFP 07

Torin 1

Reference: 10997-10

€0.00 (tax incl.)

A potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively); efficacious at a dose of 20 mg/kg in inhibiting downstream effectors of mTOR in mice

Torin 1

Reference: 10997-25

€0.00 (tax incl.)

A potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively); efficacious at a dose of 20 mg/kg in inhibiting downstream effectors of mTOR in mice

Torin 1

Reference: 10997-50

€0.00 (tax incl.)

A potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively); efficacious at a dose of 20 mg/kg in inhibiting downstream effectors of mTOR in mice

(R,S)-Anatabine

Reference: 11001-10

€0.00 (tax incl.)

A minor alkaloid produced in plants of the Solanaceae family, including tobacco; detection in urine is used as an indicator of tobacco use; diminishes Aβ production, reduces the transcription and protein levels of...

List of products by brand Cayman Chemical

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