BMS-536924

Tax included
A dual inhibitor of IGF-1R kinase and IR (IC50s = 100 and 73 nM, respectively); blocks IFG-1R autophosphorylation and signaling through MEK1/2 and Akt, leading to G1 arrest and apoptosis in ML-1 cells; reverses EMT in MCF10A cells overexpressing constitutively activated IGF-1R
Cayman Chemical
14666-10

Data sheet

Size
10 mg
CAS
468740-43-4
URL - Product
http://www.caymanchem.com/pdfs/14666.pdf