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A ceramidase inhibitor; induces cell death in SW403 colon adenocarcinoma cells in a time- and concentration-dependent manner; increases intracellular ceramide accumulation and cytochrome C release and induces apoptosis in SW403 cells; reduces tumor growth and the number of hepatic metastases in SW403 and LoVo colon cancer mouse xenograft models at 75 mg/kg
Product Details
Brand:
Cayman Chemical
Reference:
10006305-1
Data sheet
Size
1 mg
CAS
35922-06-6
URL - Product
http://www.caymanchem.com/pdfs/10006305.pdf
A ceramidase inhibitor; induces cell death in SW403 colon adenocarcinoma cells in a time- and concentration-dependent manner; increases intracellular ceramide accumulation and cytochrome C release and induces apoptosis in SW403 cells; reduces tumor growth and the number of hepatic metastases in SW403 and LoVo colon cancer mouse xenograft models at 75 mg/kg
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