Ferulenol

Prenylated 4-hydroxycoumarin. Anti-tumor compound [2]. Cytotoxic [2]. Stimulator of tubulin polymerization in vitro [2]. Inhibitor of colchicine binding to tubulin [2]. Antitubercular antibiotic with potent antibacterial activity [3]. Anti-coagulant, pro-haemorrhagic compound with higher activity than warfarin [4]. Shows hepatocyte toxicity [1, 4]. Disrupts mitochondrial membrane potential [5, 6]. Potent L-malate:quinone oxidoreductase (PfMQO) inhibitor in Plasmodium falciparum. Antimalarial.