Thapsigargin (high purity)

Intracellular Ca2+ signaling probe [1]. Specific and sensitive inhibitor of SERCA [2]. Non-TPA/PMA tumor promoter [3]. Histamine release inducer [4]. Apoptosis inducer [5, 6, 7, 8]. Mitochondrial dysfunction inducer [6, 8]. NOS modulator [9]. Angiogenesis inhibitor [10]. Stimulator of arachidonic acid metabolism in macrophages [11]. Autophagy inducer [12, 13]. TRAIL sensitizer [14]. Inducer of ER-stress in the brain.