Ubiquitin Monoclonal Antibody (Clone 6C11-B3)

Antigen: native bovine ubiquitin conjugated to KLH • Isotype: IgG2aκ • Host: mouse, clone 6C11-B3 • Cross Reactivity: (+) human, mouse, rat, and bovine ubiquitin • Application(s): WB and ELISA • Ubiquitin functions to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteasome. The ubiquitination process participates in the internalization and degradation of plasma membrane proteins and also plays a role in regulating signal transduction cascades through the elimination of inhibitor proteins.