GABAA Receptor δ subunit (N-Term) Polyclonal Antibody

Immunogen: Fusion protein from the N-terminal region of the δ subunit of rat GABAA receptor • Host: Rabbit • Species Reactivity: (+) Mouse and rat • Applications: ICC, IHC, and WB • GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. It is a multimeric subunit complex with six α's, four b’s, and four g’s, plus alternative splicing variants of some of these subunits. Several studies demonstrate that the d-subunit of the receptor may affect subunit assembly and may also confer differential sensitivity to neurosteroids and to ethanol.