anti-NLRP12 / NALP12 antibody

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
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Reference:
ARG43214
Product Details
ARG43214

Data sheet

Size
100 µL
Conjugation
Un-conjugated
Host
Rabbit
Clonality
Polyclonal
Reactivity
Human
Application
IHC-Formalin-fixed paraffin-embedded sections, Western blot
URL - Product
https://www.arigobio.com/download/datasheet/ARG43214.pdf

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