Quote anti-alpha Synuclein antibody [2A7]
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]
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Reference:
ARG43207
Brand:
ARG43207
Data sheet
- Size
- 100 µL
- Conjugation
- Un-conjugated
- Host
- Mouse
- Clonality
- Monoclonal
- Reactivity
- Human
- Clone
- 2A7
- Application
- ICC/IF, IHC-Frozen sections, IHC-Formalin-fixed paraffin-embedded sections, Western blot
- URL - Product
- https://www.arigobio.com/download/datasheet/ARG43207.pdf