A1AGP | Alpha-1-acid glycoprotein

Alpha-1-acid glycoprotein (A1AGP) or Orosomucoid (OMD) is a plasma glycoprotein synthesized by the liver. The protein is believed to regulate the interaction between blood cells and endothelial cells, and therefore also regulates the extravasation of the cells during infection and inflammation. A1AGP is a major acute phase reactant, both in man and in rat. It's concentration in blood plasma is elevated during acute inflammation, such as rheumatoid arthritis, bacterial infections, etc, and can be used for the diagnosis of inflammatory conditions.