Quote anti-Kappa Light Chain (human), Rabbit Monoclonal (RM126)
Immunoglobulins are heterotetramers composed of 2 immunoglobulin heavy and 2 immunoglobulin light chains. The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin). The light chains can be categorized into kappa type or lambda type and both are used to construct the antigen binding F(ab) region of an antibody along with the variable region of the heavy chain. The ratio of kappa and lambda light chains can be used to determine disease status by immunohistochemistry or ELISA based assays.
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Reference:
REV-31-1028-00-C100
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