DAND5 antibody [25D4]

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 28]
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Reference:
GTX53086
Brand:
Product Details
GTX53086

Data sheet

Size
100μg
Conjugation
Unconjugated
Host
Mouse
Clonality
Monoclonal
Reactivity
Human
Clone
25D4
Application
ELISA
URL - Product
https://www.genetex.com/Product/Detail/DAND5-antibody-25D4/GTX53086

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