anti-TRAIL-R1 (human), mAb (HS101)

TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
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Reference:
AG-20B-0022
Brand:
AdipoGen
Product Details
AG-20B-0022

Data sheet

Size
100 µg
Host
Purified from concentrated hybridoma tissue culture supernatant.
Clone
HS101
Application
FACS, FUNC (Blocking), ICC, IP
URL - Product
https://adipogen.com/ag-20b-0022-anti-trail-r1-human-mab-hs101.html

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