Human SCF ELISA Kit

Stem Cell Factor (SCF), also called c-kit Ligand or Mast Cell Growth Factor (MGF), is a peptide growth factor/cytokine with broad activities, especially related to hematopoiesis (ref 1-3). SCF acts on early hematopoietic progenitor/stem cells and stimulates the proliferation and survival of mast cells. Also, SCF is one of the most potent stimulators of multi-lineage progenitors (CFU-GEMM) in both human and murine bone marrow cells (ref 2,4). SCF acts synergistically with other growth factors, including erythropoietin, G-CSF, M-CSF, GM-CSF, IL-3 and IL-6, to increase the number and size of colonies of hematopoietic progenitors (ref 1,2,5). SCF appears to play an important role in the survival, proliferation or migration of primordial germ cells and melanoblasts during both development and maturation (ref 6,7).