Neutrophil (mouse) Isolation Kit Reference: 601070-1 Neutrophils are short-lived inflammatory cells that are highly adept at ingesting and destroying bacteria as part of the first line of defense in the innate immune response to many pathogenic organisms. They produce an extensive arsenal of defensive antimicrobial proteins and peptides including lysozyme, myeloperoxidase, neutrophil elastase, cathepsins, and the alpha- and beta-defensins. Neutrophils also form extracellular traps, web-like structures composed of DNA, histones, and various antimicrobial proteins that are extruded from the neutrophil in order to ensnare and kill extracellular pathogens. In mice, neutrophils comprise ~10% of circulating white blood cells, so unlike humans, it is usually not possible to isolate even one million neutrophils from a single mouse from peripheral blood. Cayman’s Neutrophil (mouse) Isolation Kit provides a streamlined method for isolating mouse neutrophils by peritoneal lavage. Included in this kit are all the reagents necessary for inducing a sterile inflammatory response in the peritoneal cavities of up to five mice, the density separation medium required to separate the neutrophils from other peritoneal leukocytes, and the fluorochrome-labeled antibodies required to assess the success of the isolation procedure by flow cytometry.
Leukotriene B4 Immunoaffinity Sorbent (50% slurry) Reference: 601301-5 For purification of leukotriene B4 from biological samples prior to analysis by ELISA or MS
Transcription Factor STAT3 Positive Control Reference: 601731-1 Transcription Factor STAT3 Positive Control has been tested and formulated to work exclusively with Cayman’s STAT3 Transcription Factor Assay Kit
Transcription Factor STAT Competitor dsDNA Reference: 601733-1 Transcription Factor STAT Competitor dsDNA has been tested and formulated to work exclusively with Cayman’s STAT3 Transcription Factor Assay Kit