Antibodies

NaveniFlex Cell MR RED

Reference: 60025

€0.00 (tax incl.)

Detect proteins, protein-protein interactions, or protein modifications in cell samples. The assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with TEX615 fluorophore is included.

NaveniFlex Cell MR Atto647N

Reference: 60017

€0.00 (tax incl.)

Detect proteins, protein-protein interactions, or protein modifications in cell samples. The NaveniFlex Cell MR Atto647N assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with...

NaveniFlex Tissue MR RED

Reference: 60027

€0.00 (tax incl.)

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with TEX615 fluorophore is included.

NaveniFlex Tissue MR Atto647N

Reference: 60026

€0.00 (tax incl.)

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with Atto647N fluorophore is included.

NaveniBright HRP

Reference: 60030

€0.00 (tax incl.)

Detect proteins, protein – protein interactions, or protein modifications. The assay is designed to be used with a mouse and a rabbit primary pair. Chromogenic readout with HRP substrate.

Naveni TriFlex Cell MR

Reference: 60024

€0.00 (tax incl.)

Detect and quantify total protein A, total protein B, and the interaction AB between the two proteins. The assay is designed to be used with a mouse and rabbit primary antibody pair.

NaveniLink

Reference: 60028

€0.00 (tax incl.)

Conjugate your own primary antibodies. The NaveniLink kit is for conjugating oligos and primary antibodies for the creation of Navenibodies. The kit is compatible with NaveniFlex Cell, NaveniFlex Tissue and NaveniBright

NaveniFlex control kit

Reference: 60029

€0.00 (tax incl.)

Control kit to identify positive signals in proximity ligation assays. Use together with NaveniFlex Cell/Tissue/Bright MR.

Naveni PD1/PD-L1 HRP

Reference: 60033

€0.00 (tax incl.)

Visualize the interaction of PD1 and PD-L1 in situ. The kit includes primary Navenibodies specific to PD1 and PD-L1, and all other reagents needed to run the assay. Chromogenic detection and bright-field read-out

Naveni PD1/PD-L1 Atto647N

Reference: 60034

€0.00 (tax incl.)

Visualize the interaction of PD1 and PD-L1 in situ. The kit includes primary Navenibodies specific to PD1 and PD-L1, and all other reagents needed to run the assay. Fluorescence readout, possible to combine with...

Naveni CD8/MHCI Atto647N

Reference: 60035

€0.00 (tax incl.)

Visualize the interaction of CD8/MHC-I in situ. The kit includes primary antibodies specific to CD8 and MHC-I, Navenibodies, and all other reagents needed to run the assay. Fluorescence readout, possible to combine...

Naveni Bright BOND RX HRP

Reference: 60031

€0.00 (tax incl.)

Detect proteins, protein – protein interactions, or protein modifications with Naveni® in situ technology using BOND RX/RXm Fully Automated Research Stainer. The kit should be used with the user’s primary antibodies...

Naveni PD1 PD-L1 BOND RX HRP

Reference: 60032

€0.00 (tax incl.)

Visualize the interaction of PD1/PD-L1 in situ using BOND RX/RXm Fully Automated Research Stainer.

NaveniFlexTM BOND RX Atto647N

Reference: 60009

€0.00 (tax incl.)

Detect proteins, protein – protein interactions, or protein modifications with Naveni® in situ technology using BOND RX/RXm Fully Automated Research Stainer. The kit should be used with the user’s primary antibodies...

NaveniFlexTM BOND RX RED

Reference: 60010

€0.00 (tax incl.)

Detect proteins, protein – protein interactions, or protein modifications with Naveni® in situ technology using BOND RX/RXm Fully Automated Research Stainer. The kit should be used with the user’s primary antibodies...

Naveni PD1/PDL1 BOND RX Atto647N

Reference: 60011

€0.00 (tax incl.)

Visualize the interaction of PD1/PD-L1 in situ using BOND RX/RXm Fully Automated Research Stainer. Detection with Atto647N fluorophore is included.

Naveni PD1/PDL1 BOND RX RED

Reference: 60012

€0.00 (tax incl.)

Visualize the interaction of PD1/PD-L1 in situ using BOND RX/RXm Fully Automated Research Stainer. Detection with Texas Red fluorophore is included.

Naveni Plex

Reference: 60000

€0.00 (tax incl.)

Naveni® Plex enables the simultaneous detection of 3 separate targets or protein-protein interactions, with enhanced specificity and sensitivity using multiplex in situ proximity ligation assay. The kit has been...

anti-Adiponectin (human), mAb (HADI 773)

Reference: AG-20A-0001

€0.00 (tax incl.)

ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte...

anti-Adiponectin (mouse), mAb (MADI 1147)

Reference: AG-20A-0003

€0.00 (tax incl.)

ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte...

anti-Resistin (mouse), mAb (MRES 06)

Reference: AG-20A-0004

€0.00 (tax incl.)

The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought...

anti-Adiponectin (mouse), mAb (MADI 04)

Reference: AG-20A-0005

€0.00 (tax incl.)

ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte...

anti-GITR (mouse), mAb (MGIT 02)

Reference: AG-20A-0007

€0.00 (tax incl.)

GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via...

anti-RELM-beta (human), mAb (HRB 149)

Reference: AG-20A-0012

€0.00 (tax incl.)

RELM-beta is a 19kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. RELM-beta has been suggested to play a regulatory role during inflammation and may also act to...

anti-Resistin (rat), mAb (RRES 07)

Reference: AG-20A-0015

€0.00 (tax incl.)

The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought...

anti-GITR (human), mAb (AIT 158D)

Reference: AG-20A-0017

€0.00 (tax incl.)

GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via...

anti-Listeria monocytogenes p60, mAb (P6007)

Reference: AG-20A-0022

€0.00 (tax incl.)

Listeria monocytogenes is a intracellular bacterium that is the causative agent of Listeriosis. It is one of the most virulent foodborne pathogens. Listeria species are known to secrete a 60-kDa protein collectively...

anti-Listeria sp. p60, mAb (P6017)

Reference: AG-20A-0023

€0.00 (tax incl.)

Listeria monocytogenes is a intracellular bacterium that is the causative agent of Listeriosis. It is one of the most virulent foodborne pathogens. Listeria species are known to secrete a 60-kDa protein collectively...

anti-FOXP3 (mouse), mAb (MF333F)

Reference: AG-20A-0025Y

€0.00 (tax incl.)

FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional...

anti-RELM-beta (mouse), mAb (MRB 46L)

Reference: AG-20A-0026

€0.00 (tax incl.)

RELM-beta is a 19kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. RELM-beta has been suggested to play a regulatory role during inflammation and may also act to...

anti-IL-23p19 (human), mAb (I 178G)

Reference: AG-20A-0027

€0.00 (tax incl.)

IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and...

anti-Tim-3 (mouse), mAb (TI 339H)

Reference: AG-20A-0029

€0.00 (tax incl.)

Tim-3 is a Th1-specific cell surface protein. It is expressed selectively by differentiated CD4+Th1 and CD8+Tc1 cells, but is absent on CD4+Th2 and CD8+ Tc2 cells. The Tim gene family has an important role in the...

anti-Tim-3 (mouse), mAb (TI 142F)

Reference: AG-20A-0030

€0.00 (tax incl.)

Tim-3 is a Th1-specific cell surface protein. It is expressed selectively by differentiated CD4+Th1 and CD8+Tc1 cells, but is absent on CD4+Th2 and CD8+ Tc2 cells. The Tim gene family has an important role in the...

anti-CD137L (human), mAb (41B436)

Reference: AG-20A-0031

€0.00 (tax incl.)

The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction...

anti-ACE2 (human), mAb (AC18F)

Reference: AG-20A-0032

€0.00 (tax incl.)

Angiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating...

anti-ACE2 (human), mAb (AC18F) (Biotin)

Reference: AG-20A-0032B

€0.00 (tax incl.)

Angiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating...

anti-Nampt (Visfatin/PBEF), mAb (OMNI379)

Reference: AG-20A-0034

€0.00 (tax incl.)

Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide...

anti-Nampt (Visfatin/PBEF), mAb (OMNI379) (Biotin)

Reference: AG-20A-0034B

€0.00 (tax incl.)

Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide...

anti-IDO (human), mAb (ID 177)

Reference: AG-20A-0035

€0.00 (tax incl.)

IDO1 is a heme enzyme that catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway, causing depletion of tryptophan which can lead to halted growth of...

anti-Adiponectin (rat), mAb (RADI 264)

Reference: AG-20A-0036

€0.00 (tax incl.)

ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte...

anti-ACE2 (human), mAb (AC384)

Reference: AG-20A-0037

€0.00 (tax incl.)

Angiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating...

anti-ACE2 (human), mAb (AC384) (Biotin)

Reference: AG-20A-0037B

€0.00 (tax incl.)

Angiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating...

anti-ANGPTL4 (human), mAb (Kairos-1)

Reference: AG-20A-0038

€0.00 (tax incl.)

ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and...

anti-ANGPTL3 (human), mAb (Kairos-37)

Reference: AG-20A-0039

€0.00 (tax incl.)

ANGPTL3 regulates angiogenesis and also directly regulates lipid, glucose, and energy metabolism.

anti-IL-33 (human), mAb (IL33305B)

Reference: AG-20A-0041

€0.00 (tax incl.)

Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human...

anti-IL-33, mAb (IL33068A)

Reference: AG-20A-0042

€0.00 (tax incl.)

Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human...

anti-IL-33, mAb (IL33026B)

Reference: AG-20A-0043

€0.00 (tax incl.)

Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human...

anti-ST2 (human), mAb (ST33868)

Reference: AG-20A-0044

€0.00 (tax incl.)

The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative...

anti-Vaspin (human), mAb (VP63)

Reference: AG-20A-0045

€0.00 (tax incl.)

Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose...

anti-ANGPTL4 (coiled-coil domain) (human), mAb (Kairos4-153AD)

Reference: AG-20A-0046

€0.00 (tax incl.)

ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and...

anti-ANGPTL4 (coiled-coil domain) (human), mAb (Kairos4-397G)

Reference: AG-20A-0047

€0.00 (tax incl.)

ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and...

anti-Ribosomal Protein S3 (human), mAb (RP159-1)

Reference: AG-20A-0048

€0.00 (tax incl.)

RpS3 is a component of the 40S ribosomal subunit and is an an essential but previously unkown subunit of NF-kappaB involved in the regulation of key genes in rapid cellular activation responses. RpS3 interacts with...

anti-Jagged-1 (human), mAb (J1G53-3)

Reference: AG-20A-0049

€0.00 (tax incl.)

Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian...

anti-Jagged-1 (human), mAb (J1G53-3) (FITC)

Reference: AG-20A-0049F

€0.00 (tax incl.)

Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian...

anti-FGF-21, mAb (FG224-7)

Reference: AG-20A-0051

€0.00 (tax incl.)

FGF-21 stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of bKlotho.

anti-ANGPTL7 (human), mAb (Kairos 108-4)

Reference: AG-20A-0053

€0.00 (tax incl.)

ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of...

anti-ANGPTL7 (human), mAb (Kairos 397-7)

Reference: AG-20A-0055

€0.00 (tax incl.)

ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of...

anti-Adiponectin (human), mAb (ADI 943)

Reference: AG-20A-0056

€0.00 (tax incl.)

ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte...

anti-DLK1 (mouse), mAb (PF105B)

Reference: AG-20A-0057

€0.00 (tax incl.)

The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting...

anti-DLK1 (mouse), mAb (PF183E)

Reference: AG-20A-0058Y

€0.00 (tax incl.)

The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting...

anti-RELM-alpha (mouse), mAb (MREL 127)

Reference: AG-20A-0060

€0.00 (tax incl.)

RELM-alpha is a member to the family of adipocyte-secreted proteins called adipocytokines. It is abundantly expressed in white adipose tissue but not in preadipocytes, nor 3T3-L1 adipocytes. RELM-alpha is involved in...

anti-RELM-alpha (rat), mAb (RREL 803)

Reference: AG-20A-0061

€0.00 (tax incl.)

RELM-alpha is a member to the family of adipocyte-secreted proteins called adipocytokines. It is abundantly expressed in white adipose tissue but not in preadipocytes, nor 3T3-L1 adipocytes. RELM-alpha is involved in...

anti-FTO, mAb (FT86-4)

Reference: AG-20A-0064

€0.00 (tax incl.)

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609...

anti-FGF-19 (human), mAb (FG98-6)

Reference: AG-20A-0065

€0.00 (tax incl.)

FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes....

anti-FGF-19 (human), mAb (FG369-1)

Reference: AG-20A-0066

€0.00 (tax incl.)

FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes....

anti-DLK1 (human), mAb (PF13-3)

Reference: AG-20A-0069

€0.00 (tax incl.)

The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting...

anti-DLK1 (human), mAb (PF299-1)

Reference: AG-20A-0070

€0.00 (tax incl.)

The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting...

anti-IL-17A (human), mAb (17-142F)

Reference: AG-20A-0071

€0.00 (tax incl.)

IL-17A exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of...

anti-IL-17A (human), mAb (17-142F) (FITC)

Reference: AG-20A-0071F

€0.00 (tax incl.)

IL-17A exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of...

anti-CD137 (mouse), mAb (M4173)

Reference: AG-20A-0072

€0.00 (tax incl.)

CD137 is a member of the tumor necrosis factor (TNF) receptor family. CD137 is expressed by activated T cells, dendritic cells, NK cells, granulocytes and cells of blood vessel walls at sites of inflammation. CD137...

anti-FGF-23 (human), mAb (FG322-3)

Reference: AG-20A-0073

€0.00 (tax incl.)

FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively...

anti-DLL1 (human), mAb (D1L165-6)

Reference: AG-20A-0074

€0.00 (tax incl.)

The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the...

anti-Sirtuin 2 (human), mAb (S2R233-1)

Reference: AG-20A-0076

€0.00 (tax incl.)

Sirtuin-2 is a NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of a-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such...

anti-Calreticulin (human), mAb (CR213-2AG)

Reference: AG-20A-0079

€0.00 (tax incl.)

Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ‘calreticulin/calnexin cycle’ that is responsible for folding and...

anti-DLL4 (human), mAb (DL86-3AG)

Reference: AG-20A-0080

€0.00 (tax incl.)

The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative...

anti-FTO (mouse), mAb (FT62-6)

Reference: AG-20A-0083

€0.00 (tax incl.)

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609...

anti-DLL1 (mouse), mAb (D1L357-1-4)

Reference: AG-20A-0085

€0.00 (tax incl.)

The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the...

anti-NQO1 (human), mAb (Skiny-1)

Reference: AG-20A-0086

€0.00 (tax incl.)

NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and...

anti-NMNAT2 (human), mAb (Nady-1)

Reference: AG-20A-0087

€0.00 (tax incl.)

NMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the...

anti-Sirtuin 6 (human), mAb (S6R82-2)

Reference: AG-20A-0091

€0.00 (tax incl.)

Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It...

anti-FTO (human), mAb (AG103)

Reference: AG-20A-0092

€0.00 (tax incl.)

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609...

anti-CTRP6 (human), mAb (256-E)

Reference: AG-20A-0093

€0.00 (tax incl.)

CTRP6 mediates the phosphorylation of AMPK and acetyl-CoA carboxylase (ACC) in skeletal muscle cells, subsequently mediating glycogen accumulation and fatty acid oxidation. It induces the expression of the potent...

anti-NS3 (HCV), mAb (1B6)

Reference: AG-20B-0001

€0.00 (tax incl.)

The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that...

anti-NS5B (HCV), mAb (5B-3B1)

Reference: AG-20B-0002

€0.00 (tax incl.)

The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that...

anti-NS5B (HCV), mAb (blocking) (5B-12B7)

Reference: AG-20B-0003

€0.00 (tax incl.)

The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that...

anti-Cardif (human), mAb (Adri-1)

Reference: AG-20B-0004

€0.00 (tax incl.)

RIG-I (retinoic acid-inducible gene I; Ddx58) and MDA5 (melanoma differentiation-associated gene 5, also known as Ifih1 or Helicard) are proteins that sense viral replication intermediates, such as double-stranded RNA...

anti-FLIP, mAb (Dave-2)

Reference: AG-20B-0005

€0.00 (tax incl.)

FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment...

anti-NLRP3/NALP3 (mouse), mAb (Cryo-1)

Reference: AG-20B-0006

€0.00 (tax incl.)

The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the...

anti-LTbetaR (mouse), mAb (4H8 WH2)

Reference: AG-20B-0008

€0.00 (tax incl.)

The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B...

anti-LTbetaR (mouse), mAb (4H8 WH2) (preservative free)

Reference: AG-20B-0008PF

€0.00 (tax incl.)

The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B...

anti-RIG-I, mAb (Alme-1)

Reference: AG-20B-0009

€0.00 (tax incl.)

RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the...

anti-RIG-I, mAb (Alme-1) (Biotin)

Reference: AG-20B-0009B

€0.00 (tax incl.)

RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the...

anti-ZBP1, mAb (Zippy-1)

Reference: AG-20B-0010

€0.00 (tax incl.)

ZBP1 is an interferon inducible protein that binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes,...