NMDA Receptor NR1 Subunit Monoclonal Antibody Reference: 10607-1 Antigen: fusion protein containing amino acids 1-564 of the NR1 subunit of rat NMDA receptor • Host: mouse • Cross Reactivity: (+) rat and mouse NMDA receptor • Application(s): IP and WB • The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ.
Tabituximab barzuxetan Reference: HY-P99581 Tabituximab barzuxetan (OTSA101-DTPA-90Y) is a radioimmunoconjugate composed of a humanized monoclonal antibody targeting FZD-10 (OTSA-101), and labeled with Yttrium 90. Tabituximab barzuxetan shows antineoplastic activity. Tabituximab barzuxetan can be used for synovial sarcoma research.
NMDA Receptor NR2A Subunit Polyclonal Antibody Reference: 10608-1 Antigen: fusion protein from the C-terminus of the NR2A subunit of rat NMDA receptor • Host: rabbit • Cross Reactivity: (+) human, mouse, and rat NMDA receptor • Application(s): IHC, IP, and WB • The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Channels with physiological activity are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
Nivolumab Reference: HY-P9903 Nivolumab is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody to treat advanced (metastatic) non-small cell lung cancer.
NMDA Receptor NR2B Subunit Polyclonal Antibody Reference: 10609-1 Antigen: fusion protein from the C-terminus of the NR2B subunit of rat NMDA receptor • Host: rabbit • Cross Reactivity: (+) human, rat, and mouse NMDA receptor • Application(s): IHC, IP, and WB • Overexpression of the NR2B-subunit of the NMDA receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression.
Apitegromab Reference: HY-P99441 Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy.