Category: Antibodies

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Reference: HY-P99340

Sotrovimab (VIR 7831) is a human IgG1κ pan-sarbecovirus monoclonal antibody (mAb), neutralizes SARS-CoV-2, SARS-CoV-1, and multiple other sarbecoviruses. Sotrovimab is developed based on S309, exhibits a long half-life and great bioavailability in the respiratory mucosa. Sotrovimab could result in immune-mediated viral clearance and prevent progression of Covid-19 early in the course of disease.

Reference: 10349-1

Host: Mouse, clone C-11 • Cross Reactivity: (+) Human cytokeratins 4, 5, 6, 8, 10, 13, and 18 • Application(s): FC and IF • Cytokeratins are intermediate filament polypeptides that provide cellular support to epithelial cells as well as contribute to more dynamic processes. Cytokeratins are differentially expressed in normal and cancer cells.

Reference: HY-P99784

Porgaviximab is a monoclonal antibody that can be used Ebola infection research.

Reference: 10381-1

Immunogen: Thioredoxin fusion protein containing amino acids 34-76 of human adropin • Host: Rabbit • Species Reactivity: (+) Human • Applications: ELISA and WB

Reference: HY-P99343

Atoltivimab (REGN3470), or maftivimab/odesivimab (Inmazeb) is the first Food and agent Administration (FDA)-approved monoclonal antibody to target Zaire ebolavirus (EBOVs) infection.