Antibodies (459)

ALDH3B2 antibody

Reference: GTX55135

€0.00 (tax incl.)

This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of...

CHML antibody

Reference: GTX55138

€0.00 (tax incl.)

The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II. [provided by...

CLCN7 antibody

Reference: GTX55139

€0.00 (tax incl.)

The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7....

Collagen VI alpha 2 antibody

Reference: GTX55141

€0.00 (tax incl.)

This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type...

COL11A1 antibody

Reference: GTX55142

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This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain....

Ephrin A4 antibody

Reference: GTX55144

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This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental...

GPR12 antibody

Reference: GTX55147

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GPR19 antibody

Reference: GTX55148

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GPR25 antibody

Reference: GTX55149

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This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. This...

GRK5 antibody

Reference: GTX55150

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This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G...

GUCY1B3 antibody

Reference: GTX55151

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This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX...

HOXB2 antibody

Reference: GTX55152

€0.00 (tax incl.)

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein...

Factor I antibody

Reference: GTX55153

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This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a...

ILF3 antibody

Reference: GTX55155

€0.00 (tax incl.)

This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF9, ILF3)...

MEOX2 antibody

Reference: GTX55157

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This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the...

MX2 antibody

Reference: GTX55158

€0.00 (tax incl.)

The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the...

MLCK antibody

Reference: GTX55159

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This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to...

NeuroD2 antibody

Reference: GTX55161

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This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which...

ORC1 antibody

Reference: GTX55162

€0.00 (tax incl.)

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds...

PI3 kinase p110 delta antibody

Reference: GTX55163

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Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks...

MED1 antibody

Reference: GTX55164

€0.00 (tax incl.)

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation...

PPP2R1B antibody

Reference: GTX55165

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This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division....

PRKAR1B antibody

Reference: GTX55166

€0.00 (tax incl.)

The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic...

RPL10 antibody

Reference: GTX55169

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This gene encodes a ribosomal protein that is a component of the 6S ribosome subunit. The related protein in chicken can bind to c-Jun and can repress c-Jun-mediated transcriptional activation. Some studies have...

RPL27A antibody

Reference: GTX55170

€0.00 (tax incl.)

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 4S subunit and a large 6S subunit. Together these subunits are composed of 4 RNA species and approximately 8 structurally distinct...

Secretogranin V antibody

Reference: GTX55171

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This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be...

ADA2a antibody

Reference: GTX55173

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Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal...

TSG6 antibody

Reference: GTX55175

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The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved...

Uromucoid antibody

Reference: GTX55176

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The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl...

CYLN2 antibody

Reference: GTX55177

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The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was...

MTERF antibody

Reference: GTX55178

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This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S...

LZTR1 antibody

Reference: GTX55179

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This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein...

B3GALT1 antibody

Reference: GTX55180

€0.00 (tax incl.)

This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates...

LRAT antibody

Reference: GTX55182

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The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A...

RECQL4 antibody

Reference: GTX55183

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The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is...

EIF5B antibody

Reference: GTX55185

€0.00 (tax incl.)

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors...

MLL4 antibody

Reference: GTX55187

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This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain....

COX17 antibody

Reference: GTX55188

€0.00 (tax incl.)

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3...

PGRMC2 antibody

Reference: GTX55189

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DBF4 antibody

Reference: GTX55192

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GPR75 antibody

Reference: GTX55193

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GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 22]

RAB40B antibody

Reference: GTX55194

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The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 28]

FAIM2 antibody

Reference: GTX55195

€0.00 (tax incl.)

GPCR G2A antibody

Reference: GTX55201

€0.00 (tax incl.)

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate...

Neurotrimin antibody

Reference: GTX55202

€0.00 (tax incl.)

This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite...

GPRC5B antibody

Reference: GTX55203

€0.00 (tax incl.)

This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion...

SENP7 antibody

Reference: GTX55205

€0.00 (tax incl.)

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 61912) is required for many cellular processes. SUMO-specific proteases, such as SENP7,...

SCAF1 antibody

Reference: GTX55206

€0.00 (tax incl.)

DCLRE1B antibody

Reference: GTX55207

€0.00 (tax incl.)

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of...

Microcephalin antibody

Reference: GTX55208

€0.00 (tax incl.)

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have...

MED30 antibody

Reference: GTX55209

€0.00 (tax incl.)

The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED3 is a component of this complex that appears to be metazoan specific (Baek et al., 22...

ARRDC1 antibody

Reference: GTX55210

€0.00 (tax incl.)

SUHW1 antibody

Reference: GTX55211

€0.00 (tax incl.)

This gene encodes a zinc finger protein. The encoded protein contains 4 C2H2-type zinc fingers, which are commonly found in transcription factors. A variety of functions may be performed by this type of zinc finger...

RNF113B antibody

Reference: GTX55212

€0.00 (tax incl.)

RPL10L antibody

Reference: GTX55213

€0.00 (tax incl.)

This gene encodes a protein sharing sequence similarity with ribosomal protein L1. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is...

GPR110 antibody

Reference: GTX55215

€0.00 (tax incl.)

COX8A antibody

Reference: GTX55216

€0.00 (tax incl.)

The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical...

IPP1 antibody

Reference: GTX55217

€0.00 (tax incl.)

CDKL5 antibody

Reference: GTX55218

€0.00 (tax incl.)

This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also...

UBR2 antibody

Reference: GTX55219

€0.00 (tax incl.)

This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative...

ZO-3 antibody

Reference: GTX55220

€0.00 (tax incl.)

The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single...

BARD1 antibody

Reference: GTX55221

€0.00 (tax incl.)

This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the...

GAS8 antibody

Reference: GTX55223

€0.00 (tax incl.)

This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is...

HEXB antibody

Reference: GTX55224

€0.00 (tax incl.)

Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing...

ELOVL4 antibody

Reference: GTX55225

€0.00 (tax incl.)

This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor...

ZNF174 antibody

Reference: GTX55226

€0.00 (tax incl.)

This gene encodes a protein with three Cys2-His2-type zinc fingers in the carboxy-terminus, a putative nuclear localization signal, and an amino-terminus SCAN box which forms homodimers. This protein is believed to...

CRMP3 antibody

Reference: GTX55228

€0.00 (tax incl.)

HBP1 antibody

Reference: GTX55229

€0.00 (tax incl.)

Casein Kinase 1 gamma antibody

Reference: GTX55230

€0.00 (tax incl.)

This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle...

CARD14 antibody

Reference: GTX55231

€0.00 (tax incl.)

This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are...

SHARP1 antibody

Reference: GTX55232

€0.00 (tax incl.)

This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTLs...

USP32 antibody

Reference: GTX55233

€0.00 (tax incl.)

BTF3L4 antibody

Reference: GTX55234

€0.00 (tax incl.)

CEP41 antibody

Reference: GTX55235

€0.00 (tax incl.)

This gene encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles...

BAI3 antibody

Reference: GTX55237

€0.00 (tax incl.)

This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and...

GPR116 antibody

Reference: GTX55241

€0.00 (tax incl.)

GPR143 antibody

Reference: GTX55242

€0.00 (tax incl.)

This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in...

GPR152 antibody

Reference: GTX55243

€0.00 (tax incl.)

GPR85 antibody

Reference: GTX55244

€0.00 (tax incl.)

Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters,...

IL20 Receptor alpha antibody

Reference: GTX55245

€0.00 (tax incl.)

This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 2, a cytokine that may be involved in epidermal function. The interleukin 2 receptor...

Latrophilin 2 antibody

Reference: GTX55247

€0.00 (tax incl.)

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a...

p107 antibody

Reference: GTX55251

€0.00 (tax incl.)

The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell...

RPA4 antibody

Reference: GTX55252

€0.00 (tax incl.)

This gene encodes a single-stranded DNA-binding protein that is the 3-kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle...

ZNF496 antibody

Reference: GTX55254

€0.00 (tax incl.)

Osteocalcin antibody

Reference: GTX55255

€0.00 (tax incl.)

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in...

Cadherin 19 antibody

Reference: GTX55258

€0.00 (tax incl.)

This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin...

CDK2AP1 antibody

Reference: GTX55259

€0.00 (tax incl.)

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This...

DGKE antibody

Reference: GTX55262

€0.00 (tax incl.)

Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells,...

EBI3 antibody

Reference: GTX55263

€0.00 (tax incl.)

This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with...

FGF6 antibody

Reference: GTX55265

€0.00 (tax incl.)

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological...

GPR123 antibody

Reference: GTX55266

€0.00 (tax incl.)

This gene encodes a protein that belongs to the adhesion family of G-protein-coupled receptors. Members of this family function in several sensory systems and regulate blood pressure, immune responses, food intake and...

GTPBP5 antibody

Reference: GTX55267

€0.00 (tax incl.)

Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal...

Beta-glucuronidase antibody

Reference: GTX55268

€0.00 (tax incl.)

This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in...

MEKK4 antibody

Reference: GTX55270

€0.00 (tax incl.)

The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase...

XTP4 antibody

Reference: GTX55271

€0.00 (tax incl.)

OVOL1 antibody

Reference: GTX55272

€0.00 (tax incl.)

This gene encodes a putative zinc finger containing transcription factor that is highly similar to homologous protein in Drosophila and mouse. Based on known functions in these species, this protein is likely involved...

PFKFB2 antibody

Reference: GTX55273

€0.00 (tax incl.)

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a...

PTTG1IP antibody

Reference: GTX55274

€0.00 (tax incl.)

This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein...

ROBO2 antibody

Reference: GTX55278

€0.00 (tax incl.)

The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit...

RSK4 antibody

Reference: GTX55279

€0.00 (tax incl.)

This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as...

Category: Antibodies

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