Infliximab Reference: HY-P9970 Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2). Infliximab has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research.
HRP-conjugated GAPDH Mouse mAb Reference: AC035 This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.
IHCeasy CD68 Ready-To-Use IHC Kit Reference: KHC0006 KHC0006 is a ready-to-use IHC kit for staining of CD68. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
11β-Hydroxysteroid Dehydrogenase (Type 2) Polyclonal Antibody Reference: 10004549-1 Immunogen: Synthetic peptide from the N-terminal region of human 11β-HSD2; Host: Rabbit; Species Reactivity: (+) Human, mouse, and rat; Application(s): IHC and WB
Biotin Goat Anti-Human IgG (H+L) Antibody Reference: K1218-2 Biotin-conjugated Affinity Purified Goat anti-Human IgG (H+L)
Lacnotuzumab Reference: HY-P99368 Lacnotuzumab (MCS110) is a neutralizing humanized IgG1/κ monoclonal antibody targeting CSF-1 that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis.
GAPDH (Human Specific) Rabbit mAb Reference: AC036 This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.
IHCeasy CD31 Ready-To-Use IHC Kit Reference: KHC0022 KHC0022 is a ready-to-use IHC kit for staining of CD31. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
CD45 Monoclonal Antibody (Clone BRA-55) Reference: 10004597-1 Immunogen: Human CD45 • Host: Mouse • Species Reactivity: (+) Human • Applications: FC, WB, ICC, IHC • MW = 170-220 kDa
Biotin Goat Anti-Rabbit IgG (H+L) Antibody Reference: K1219-1 Biotin-conjugated Affinity Purified Goat anti-Rabbit IgG (H+L)
Laprituximab Reference: HY-P99684 Laprituximab (J2898A) is a humanized IgG1 anti-EGFR antibody that can be used for the synthesis of ADC IMGN289.