TRAIL-R1 to -R4 Flow Cytometry Pack Reference: AG-44B-0004 TRAIL-R1, -R2, -R3 and -R4 are receptors for the cytotoxic ligand TRAIL. When signaling through TRAIL-R1 and -R2, the adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. They promote the activation of NF-kappaB. TRAIL-R3 lacks a cytoplasmic death domain, and TRAIL-R4 contains a truncated death domain, and hence are not capable of inducing apoptosis. They protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Acetyltransferase Assay Buffer Reference: A01-09-01 5X stock solution of the buffer used for assaying histone acetyltransferases (KAT).
Acetyltransferase Assay Buffer Reference: A01-09-05 5X stock solution of the buffer used for assaying histone acetyltransferases (KAT).
Acetyltransferase Assay Buffer Reference: A01-09-20 5X stock solution of the buffer used for assaying histone acetyltransferases (KAT).
Acetyltransferase Dilution Buffer Reference: A21-09-01 Solution of buffer used for diluting enzyme histone acetyltransferases (KAT).
Acetyltransferase Dilution Buffer Reference: A21-09-05 Solution of buffer used for diluting enzyme histone acetyltransferases (KAT).
Acetyltransferase Dilution Buffer Reference: A21-09-20 Solution of buffer used for diluting enzyme histone acetyltransferases (KAT).
ATP Stock Solution Reference: A50-09-200 10 mM ATP Stock Solution used for preparing hot ATP assay cocktail.
Ca2+/Calmodulin Solution II, 10x Reference: C02-39B-500 10x stock solution used for assaying activity of calcium-calmodulin-activated protein kinase enzymes.